Scrabble
Permanent link to this comic: http://xkcd.com/492/
Image URL (for hotlinking/embedding): http://imgs.xkcd.com/comics/scrabble.png
[[A first-person view of a family scrabble game at a table. The two letters on the board are 'HI' and the letters in your hand are 'CLTORIS']]
This always happens to me in family scrabble games.
{{title text: A veteran Scrabble player will spot the 'OSTRICH' option.}}